Xenobiotica

Altered hepatic drug-metabolizing activity in rats suffering from hypoxemia with experimentally induced acute lung impairment

Bisphenol S modulates concentrations of bisphenol A and oestradiol in female and male mice

The impact of azole antifungal drugs on imatinib metabolism in human liver microsomes

Functionally relevant genetic variants of glutathione S-transferase GSTM5 in cynomolgus and rhesus macaques

In vitro inhibitory effects of sophocarpine on human liver cytochrome P450 enzymes

Metabonomics analysis of serum from rats given long-term and low-level cadmium by ultra-performance liquid chromatography-mass spectrometry

Disposition of [C-14]hydroquinone in Harlan Sprague-Dawley rats and B6C3F1/N mice: species and route comparison

Application of unbound liver-to-plasma concentration ratio to quantitative projection of cytochrome P450-mediated drug-drug interactions using physiologically based pharmacokinetic modelling approach

Evaluation of the inhibition of human carboxylesterases (CESs) by the active ingredients from Schisandra chinensis

Gut microbiota metabolizes nabumetone in vitro: Consequences for its bioavailability in vivo in the rodents with altered gut microbiome