Biopharmaceutics & Drug Disposition

Pharmacokinetics and tissue distribution of 4-diaminopyridine in rats

Biopharmaceutics classification and intestinal absorption of chikusetsusaponin IVa

Pharmacokinetic and pharmacodynamic model for analysis of adalimumab administered for Crohn's disease

Profiling of hepatic metabolizing enzymes and nuclear receptors in rats with adjuvant arthritis by targeted proteomics

Effects of renal impairment on transporter-mediated renal reabsorption of drugs and renal drug-drug interactions: A simulation-based study

Species differences in metabolism of a new antiepileptic drug candidate, DSP-0565 [2-(2 '-fluoro[1 '-biphenyl]-2-yl)acetamide]

Strain-specific altered nicotine metabolism in 3 '-diindolylmethane (DIM) exposed mice

Theoretical consideration of the properties of intestinal flow models on route-dependent drug removal: Segregated Flow (SFM) vs. Traditional (TM)

Metabolism of steroids by cytochrome P450 2C9 variants

CYP3A but not P-gp plays a relevant role in the in vivo intestinal and hepatic clearance of the delta-specific phosphoinositide-3 kinase inhibitor leniolisib