Chemical Biology & Drug Design

Discovery of novel pyrrolopyrimidine/pyrazolopyrimidine derivatives bearing 3-triazole moiety as c-Met kinase inhibitors

Design and optimize N-substituted EF24 as effective and low toxicity NF-kappa B inhibitor for lung cancer therapy via apoptosis-to-pyroptosis switch

Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors by exploring the structure-activity relationship of solvent-exposed regions I

Discovery of two bombinin peptides with antimicrobial and anticancer activities from the skin secretion of Oriental fire-bellied toad, Bombina orientalis

The applications of PCA in QSAR studies: A case study on CCR5 antagonists

New hydrazide-hydrazones of isonicotinic acid: synthesis, lipophilicity and in vitro antimicrobial screening

Biological activities of 5-trihydroxypiperidines and their N- and O-derivatives

Cucurbitacin-B attenuates CCl4-induced hepatic fibrosis in mice through inhibition of STAT-3

Prediction and validation of potent peptides against herpes simplex virus type 1 via immunoinformatic and systems biology approach

Screening of curcumin-derived isoxazole, pyrazoles, and pyrimidines for their anti-inflammatory, antinociceptive, and cyclooxygenase-2 inhibition