《Genes And Diseases》期刊

杂志介绍

中科院分区

1区

CiteScore

10.4

期刊收录

SCIE

Genes And Diseases（中文译名：《基因与疾病》），ISSN：2352-3042，是Elsevier出版的国际性学术期刊，该刊采用非OA开放访问，学科归属为Biochemistry, Genetics and Molecular Biology - Biochemistry。该刊是医学、生化与分子生物学领域的国际权威刊物，已被SCIE（科学引文索引扩展版）等国际主流学术数据库收录。2025年期刊CiteScore为10.4，在中科院期刊分区体系中位列医学大类1区，在所属学科领域具备高学术影响力与国际认可度。Genes And Diseases长期聚焦医学、生化与分子生物学及相关产业的技术应用前沿，平均审稿周期35 Weeks，审稿流程高效稳定。在稿件录用评判中，该刊将创新性与前沿性作为核心遴选标准，重点收录能够对医学、生化与分子生物学领域的落地与发展产生实质性推动价值的研究成果。

期刊评价

名词解释：

影响因子（Impact Factor, IF）：指该期刊前两年发表的文章，在第三年的平均被引用次数。它反映了期刊的近期平均影响力和热度。

中科院分区：中科院分区表是国内主流的学术期刊分级评价工具，核心意义是建立跨学科可比的统一评价标尺，为职称评审、学位授予、科研立项等科研管理工作提供标准化量化依据，同时帮助科研人员筛选优质期刊、规避学术风险，适配国内本土化的科研评价需求。

期刊分区表

《新锐期刊分区表》（2026年3月发布）

大类学科	小类学科	Top期刊	综述期刊
医学 1区	BIOCHEMISTRY & MOLECULAR BIOLOGY 生化与分子生物学 GENETICS & HEREDITY 遗传学 1区 1区	否	否

期刊分区表（2025年3月升级版）

大类学科	小类学科	Top期刊	综述期刊
医学 2区	BIOCHEMISTRY & MOLECULAR BIOLOGY 生化与分子生物学 GENETICS & HEREDITY 遗传学 2区 2区	否	否

期刊分区表（2023年12月升级版）

大类学科	小类学科	Top期刊	综述期刊
医学 2区	BIOCHEMISTRY & MOLECULAR BIOLOGY 生化与分子生物学 GENETICS & HEREDITY 遗传学 2区 2区	否	否

中国学者近期发文

Lactylation-driven therapeutic resistance in cancer: Mechanisms and therapeutic opportunitie

Author:Zhang, Wanghao; Huang, Guanglong; Tang, Woheng; Li, Jiaxian; Chen, Jingxian; Feng, Yaojiang; Li, Kaichen; Pan, Can; Li, Shunshen; Zhang, Huayang; Ye, Rongxu; Long, Hao; Yi, Guo-zhong

Journal: GENES & DISEASES. 2026; Vol. 13, Issue 4, pp. -. DOI: 10.1016/j.gendis.2025.101935

Understanding nerve-tumor interactions: From basic biology to therapeutic innovatio

Author:Sun, Liangzhan; Li, Xia; Wang, Yaxuan; Wang, Jingxuan; Xie, Renrui; Zhang, Ningyi; Zhang, Zemin

Journal: GENES & DISEASES. 2026; Vol. 13, Issue 4, pp. -. DOI: 10.1016/j.gendis.2025.101955

Lgr

Author:Li, Han; Guan, Xiaoqi; Wang, Yu; Guo, Haidong

Journal: GENES & DISEASES. 2026; Vol. 13, Issue 4, pp. -. DOI: 10.1016/j.gendis.2025.101863

Selenoproteins: Minute yet vital players governing cellular fat

Author:Xia, Chaoyi; Wu, Yifan; Zhang, Haoming; Qin, Lang; Hu, Yiren; Fu, Caiyun

Journal: GENES & DISEASES. 2026; Vol. 13, Issue 4, pp. -. DOI: 10.1016/j.gendis.2025.101938

Emerging roles of the metabolic regulator 3-hydroxy-3-methylglutaryl coenzyme-CoA reductase in human cancers: From biology to therapeutic

Author:Li, Wenfang; Xu, Jianxiong; Long, Yuxuan; Zhang, Han; Rong, Xiaojuan; Su, Zhengding

Journal: GENES & DISEASES. 2026; Vol. 13, Issue 4, pp. -. DOI: 10.1016/j.gendis.2025.101945

Intra-tumoral microbiota: Key modulators of tumor immunity and therapeutic potentia

Author:He, Junju; Tan, Hui; Qiu, Yanru; Dan, Yuchao; Wan, Qian; Li, Lan; Wu, Jie; Song, Qibin; Chen, Hongbin; Xu, Bin

Journal: GENES & DISEASES. 2026; Vol. 13, Issue 4, pp. -. DOI: 10.1016/j.gendis.2025.101963

Suppression of UCP2 alleviates leukemogenesis by enhancing branched-chain amino acids-induced oxidative stress via activating the PI3K/AKT/ mTOR signaling pathwa

Author:Innocent, Agida Okohi; Shen, Yajie; Gao, Yixuan; Sun, Ruixin; Aximujiang, Kasimujiang; Xu, Zizhen; Cheng, Jinke; Ma, Jiao

Journal: GENES & DISEASES. 2026; Vol. 13, Issue 4, pp. -. DOI: 10.1016/j.gendis.2025.101794

Elevated diurnal CD36 expression disrupts the bile acid synthesis rhythm leading to cholestatic liver injury and inflammation via the HMGCR/CYP7A1 axi

Author:Zhang, Yang; Zhang, Mingyang; Fu, Shuning; Wang, Zhenyu; Zhao, Yunfei; Gong, Junhua; Chen, Miao; Zhang, Nuo; Chen, Mengyue; Ruan, Xiong Z.; Chen, Yaxi

Journal: GENES & DISEASES. 2026; Vol. 13, Issue 4, pp. -. DOI: 10.1016/j.gendis.2025.101776

PDK1 elevation was induced by epigenetic modifications of KDM3A and METTL16 to mediate TKI resistance and cancer developmen

Author:Zhou, Zhihao; Zhang, Ruike; Zhang, Zhaoyang; Zhang, Liyuan; Wang, Wei; Liu, Wenjing; Zhang, Chunyang; Lin, Gen; Yu, Weimiao; Xu, Bo; Wang, Lin; Jiang, Bing-Hua

Journal: GENES & DISEASES. 2026; Vol. 13, Issue 4, pp. -. DOI: 10.1016/j.gendis.2025.101947

CD14 +CXCL10+ monocytes are associated with peripheral immune network alterations in systemic juvenile idiopathic arthritis: From multiple center

Author:Luo, Qiang; Yang, Jun; Yu, Haiguo; Hao, Han; Wu, Xinglin; Luo, Xiwen; Ma, Mingsheng; Yang, Xi; Zhang, Zhiyong; An, Yunfei; Zhao, Xiaodong; Song, Hongmei; Tang, Xuemei

Journal: GENES & DISEASES. 2026; Vol. 13, Issue 4, pp. -. DOI: 10.1016/j.gendis.2025.101942